Australia beat England in first Ashes Test to go 1-0 up in the five-match series at The Gabba in Brisbane. On Day 4, Australia needed just 20 runs in the fourth innings to win the clash and they did it in just the sixth over of the match.
Resuming from 220/2 in 70 overs, England fall short and were bowled out for 297 runs. Captain Joe Root was the best batter from the English lineup with his 89 runs.
Off-spinner Lyon became the 17th bowler to reach the milestone, and the third Australian, after Shane Warne and Glenn McGrath.
After his agonising wait of 326 days to reach the milestone, Lyon got his 401st wicket in a matter of few minutes, dismissing Ollie Pope, who gloved a catch to first slip, for just four.
Brief scores: England 147 & 297 in 103 overs (Joe Root 89, Dawid Malan 82; Pat Cummins 2/51, Mitchell Starc 1/77; Nathan Lyon 4/91, Cameron Green 2/23) lost to Australia 425 and 20/1 in 5.1 overs (Marcus Harris 9 not out, Ollie Robinson 1/13) by nine wickets.